Submission Details

Molecule(s):
COc1ccc(-c2cccc(S(=O)(=O)N3CCN(C(C)=O)CC3)c2)cc1

ANT-OPE-7824651a-1

COc1ccc(-c2cccc(S(=O)(=O)N3CCN(C(C)=O)CC3)c2)cc1

CC(=O)N1CCN(S(=O)(=O)c2cccc(-c3ccccc3)c2)CC1

ANT-OPE-7824651a-2

CC(=O)N1CCN(S(=O)(=O)c2cccc(-c3ccccc3)c2)CC1


Design Rationale:

Attempted modification of fragment 0769 done by eye - exterior of pocket should be able to fit another phenyl ring in nicely

Inspired By:
Discussion: