Submission Details

YIA-UNI-71f25a82
Molecule(s):
N[C@H](Cc1c[nH]c2ccccc12)C(=O)NN(Cc1ccccc1)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)O

YIA-UNI-71f25a82-1

N[C@H](Cc1c[nH]c2ccccc12)C(=O)NN(Cc1ccccc1)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)O

CC(C)C[C@H](NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)CN(N)Cc1ccccc1)C(=O)O

YIA-UNI-71f25a82-2

CC(C)C[C@H](NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)CN(N)Cc1ccccc1)C(=O)O

Design Rationale:

The above compounds are trypsin inhibitors. You can find more in this publication. https://www.sciencedirect.com/science/article/abs/pii/S0008622309005338

Inspired By:
Discussion:

Contributor: Yiannis Sarigiannis, University of Nicosia - Wed, 25 Mar 2020 15:42:02 +0000