Submission Details

NIM-UNI-6eebfcd4
Molecule(s):
O=C(CCl)CN(C(=O)Nc1ccccc1)c1cncc(CCNC(=O)c2cccc(Cl)c2)c1

NIM-UNI-6eebfcd4-1

O=C(CCl)CN(C(=O)Nc1ccccc1)c1cncc(CCNC(=O)c2cccc(Cl)c2)c1

3-aminopyridine-like Check Availability on Manifold View
O=C(CCl)CNc1cncc(CCNC(=O)c2cccc(Cl)c2)c1

NIM-UNI-6eebfcd4-2

O=C(CCl)CNc1cncc(CCNC(=O)c2cccc(Cl)c2)c1

Design Rationale:

Merging fragments 426 and 434, and using fragment 770 to position an alpha chloro substituent in the correct position.

Inspired By:
Discussion:

Contributor: Nimesh Mistry, University of Leeds - Tue, 31 Mar 2020 21:49:16 +0000