Submission Details

EDJ-MED-6e43a462
Molecule(s):
COc1ccn2c(NC(=O)Cc3cccc(Cl)c3)cnc2c1

EDJ-MED-6e43a462-1

COc1ccn2c(NC(=O)Cc3cccc(Cl)c3)cnc2c1

3-aminopyridine-like Assayed Check Availability on Manifold View
COc1ccc2ncc(NC(=O)Cc3cccc(Cl)c3)n2c1

EDJ-MED-6e43a462-2

COc1ccc2ncc(NC(=O)Cc3cccc(Cl)c3)n2c1

3-aminopyridine-like Assayed Check Availability on Manifold View
COc1cccc2ncc(NC(=O)Cc3cccc(Cl)c3)n12

EDJ-MED-6e43a462-3

COc1cccc2ncc(NC(=O)Cc3cccc(Cl)c3)n12

3-aminopyridine-like Assayed Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1cnc2ncccn12

EDJ-MED-6e43a462-4

O=C(Cc1cccc(Cl)c1)Nc1cnc2ncccn12

3-aminopyridine-like Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1cnc2cnccn12

EDJ-MED-6e43a462-5

O=C(Cc1cccc(Cl)c1)Nc1cnc2cnccn12

3-aminopyridine-like Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1cnc2ccncn12

EDJ-MED-6e43a462-6

O=C(Cc1cccc(Cl)c1)Nc1cnc2ccncn12

3-aminopyridine-like Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1cnc2cccnn12

EDJ-MED-6e43a462-7

O=C(Cc1cccc(Cl)c1)Nc1cnc2cccnn12

3-aminopyridine-like Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1cnc2ccc(F)cn12

EDJ-MED-6e43a462-8

O=C(Cc1cccc(Cl)c1)Nc1cnc2ccc(F)cn12

3-aminopyridine-like Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1cnc2ccc(Cl)cn12

EDJ-MED-6e43a462-9

O=C(Cc1cccc(Cl)c1)Nc1cnc2ccc(Cl)cn12

3-aminopyridine-like Check Availability on Manifold View
Nc1ccc2ncc(NC(=O)Cc3cccc(Cl)c3)n2c1

EDJ-MED-6e43a462-10

Nc1ccc2ncc(NC(=O)Cc3cccc(Cl)c3)n2c1

3-aminopyridine-like Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1cnc2n1CCCC2

EDJ-MED-6e43a462-11

O=C(Cc1cccc(Cl)c1)Nc1cnc2n1CCCC2

3-aminopyridine-like Assayed Check Availability on Manifold View
CNc1ccc2ncc(NC(=O)Cc3cccc(Cl)c3)n2c1

EDJ-MED-6e43a462-12

CNc1ccc2ncc(NC(=O)Cc3cccc(Cl)c3)n2c1

3-aminopyridine-like Check Availability on Manifold View
CN(C)c1ccc2ncc(NC(=O)Cc3cccc(Cl)c3)n2c1

EDJ-MED-6e43a462-13

CN(C)c1ccc2ncc(NC(=O)Cc3cccc(Cl)c3)n2c1

3-aminopyridine-like Check Availability on Manifold View
Design Rationale:

Analogues of PET-UNK-8df914d1-2 aiming for higher potency

Discussion:

Contributor: Ed J Griffen, MedChemica Ltd - Thu, 03 Jun 2021 15:19:57 +0000