Submission Details

Molecule(s):
O=C1N(c2cncc3ccccc23)CCC12CNc1ccc(Cl)cc12

DAR-DIA-6be260fc-1

O=C1N(c2cncc3ccccc23)CCC12CNc1ccc(Cl)cc12

3-aminopyridine-like Check Availability on Manifold View
CC(C)C[C@H]1CN(c2cncc3ccccc23)C(=O)C12CNc1ccc(Cl)cc12

DAR-DIA-6be260fc-2

CC(C)C[C@H]1CN(c2cncc3ccccc23)C(=O)C12CNc1ccc(Cl)cc12

3-aminopyridine-like Check Availability on Manifold View
C[C@H]1CN(c2cncc3ccccc23)C(=O)C12CNc1ccc(Cl)cc12

DAR-DIA-6be260fc-3

C[C@H]1CN(c2cncc3ccccc23)C(=O)C12CNc1ccc(Cl)cc12

3-aminopyridine-like Check Availability on Manifold View
CC(C)[C@H]1CN(c2cncc3ccccc23)C(=O)C12CNc1ccc(Cl)cc12

DAR-DIA-6be260fc-4

CC(C)[C@H]1CN(c2cncc3ccccc23)C(=O)C12CNc1ccc(Cl)cc12

3-aminopyridine-like Check Availability on Manifold View
O=C1N(c2cncc3ccccc23)CCC12CCNc1ccc(Cl)cc12

DAR-DIA-6be260fc-5

O=C1N(c2cncc3ccccc23)CCC12CCNc1ccc(Cl)cc12

3-aminopyridine-like Check Availability on Manifold View
O=C1N(c2cncc3ccccc23)CCCC12CNc1ccc(Cl)cc12

DAR-DIA-6be260fc-6

O=C1N(c2cncc3ccccc23)CCCC12CNc1ccc(Cl)cc12

3-aminopyridine-like Check Availability on Manifold View

Design Rationale:

Spirocyclic analogues of isoquinoline series.

Inspired By:
Discussion: