ChloroAcetAmide is a recognised covalent warhead. We docked using an enhanced version of our THINK software (https://treweren.com) approximately 1000 such molecules from the Enamine building block collection (which were consequently of relatively low molecular mass). We required interactions at two other residues in addition to binding covalently to CYS(145). This is a sample of the best 100 docked molecules.
A SD file of the docked coordinates is available.