Submission Details

SEA-TRI-67e8f1c7
Molecule(s):
O=C(CCl)N1CCN(Cc2cc(Cl)cc3cccc(OCCN4CCOCC4)c23)CC1

SEA-TRI-67e8f1c7-1

O=C(CCl)N1CCN(Cc2cc(Cl)cc3cccc(OCCN4CCOCC4)c23)CC1

piperazine-chloroacetamide Ordered Check Availability on Manifold View
Design Rationale:

Fragment extension into lipophilic pocket (Cl group) Solubilisation

Other Notes:

SMcK-018

Inspired By:
Discussion:

Contributor: Sean McKenna, Trinity College Dublin - Thu, 02 Apr 2020 10:08:26 +0000