Submission Details

MIC-UNK-67d4a29a
Molecule(s):
CN(C(=O)Cc1cccc(Cl)c1)c1cncc2cccc(Cl)c12

MIC-UNK-67d4a29a-1

CN(C(=O)Cc1cccc(Cl)c1)c1cncc2cccc(Cl)c12

3-aminopyridine-like Check Availability on Manifold View
CN(C(=O)Cc1cccc(Cl)c1)c1cncc2cccc(F)c12

MIC-UNK-67d4a29a-2

CN(C(=O)Cc1cccc(Cl)c1)c1cncc2cccc(F)c12

3-aminopyridine-like Check Availability on Manifold View
Cc1cccc2cncc(N(C)C(=O)Cc3cccc(Cl)c3)c12

MIC-UNK-67d4a29a-3

Cc1cccc2cncc(N(C)C(=O)Cc3cccc(Cl)c3)c12

3-aminopyridine-like Check Availability on Manifold View
COc1cccc2cncc(N(C)C(=O)Cc3cccc(Cl)c3)c12

MIC-UNK-67d4a29a-4

COc1cccc2cncc(N(C)C(=O)Cc3cccc(Cl)c3)c12

3-aminopyridine-like Check Availability on Manifold View
Design Rationale:

Simplified versions of MIC-UNK-50cce87d as N-methyl substituent shouldn't decrease potency in this case

Discussion:

Contributor: Michal K - Mon, 26 Oct 2020 14:35:24 +0000