Submission Details

Molecule(s):
O=C(/C=C/c1cccs1)N1CCN(S(=O)(=O)c2c(F)cccc2F)CC1

NAU-LAT-64f4b287-1

O=C(/C=C/c1cccs1)N1CCN(S(=O)(=O)c2c(F)cccc2F)CC1

O=C(/C=C/c1cccs1)N1CCN(S(=O)(=O)Cc2ccon2)CC1

NAU-LAT-64f4b287-2

O=C(/C=C/c1cccs1)N1CCN(S(=O)(=O)Cc2ccon2)CC1

O=C(CCl)N1CCN(Cc2nc(-c3cccs3)no2)CC1

NAU-LAT-64f4b287-3

O=C(CCl)N1CCN(Cc2nc(-c3cccs3)no2)CC1

piperazine-chloroacetamide Made Check Availability on Manifold View
COc1ccc2c(c1)CN(C(=O)CCl)C(c1ccccc1)C2

NAU-LAT-64f4b287-4

COc1ccc2c(c1)CN(C(=O)CCl)C(c1ccccc1)C2

Cc1nnc(C2Cc3ccccc3CN2C(=O)CCl)o1

NAU-LAT-64f4b287-5

Cc1nnc(C2Cc3ccccc3CN2C(=O)CCl)o1

O=C(Cc1ccc(O)cc1)Nc1cccc2cc[nH]c12

NAU-LAT-64f4b287-6

O=C(Cc1ccc(O)cc1)Nc1cccc2cc[nH]c12

3-aminopyridine-like Made Check Availability on Manifold View
O=C(Cc1ccc(F)cc1)Nc1cccc2cc[nH]c12

NAU-LAT-64f4b287-7

O=C(Cc1ccc(F)cc1)Nc1cccc2cc[nH]c12

3-aminopyridine-like Made Check Availability on Manifold View
O=C(Nc1ccccc1)c1ccc2[nH]ccc2c1

NAU-LAT-64f4b287-8

O=C(Nc1ccccc1)c1ccc2[nH]ccc2c1

NC(=O)C1CCCN1CC(=O)Nc1cccnc1

NAU-LAT-64f4b287-10

NC(=O)C1CCCN1CC(=O)Nc1cccnc1

3-aminopyridine-like Ordered Check Availability on Manifold View

Design Rationale:

X-ray/IC50 fragment and structure growing/merging by eye. All submitted compounds should be purchasable from Enamine.

Inspired By:
Discussion: