Submission Details

ROB-UNI-611831f5
Molecule(s):
Nc1cc(Oc2cc(Cl)cc(CC(=O)Nc3cncc4ccccc34)c2)c[nH]c1=O

ROB-UNI-611831f5-1

Nc1cc(Oc2cc(Cl)cc(CC(=O)Nc3cncc4ccccc34)c2)c[nH]c1=O

3-aminopyridine-like Check Availability on Manifold View
O=C(Nc1cncc2ccccc12)C1CCNc2ncc(Cl)cc21

ROB-UNI-611831f5-2
Duplicate of:
ALP-POS-fe871b40-6

O=C(Nc1cncc2ccccc12)C1CCNc2ncc(Cl)cc21

Duplicate 3-aminopyridine-like Ordered Check Availability on Manifold View
Design Rationale:

Potential beta-lactam replacement and pyridine seeking Bifurcated H-Bond (with Asn in the protein)

Discussion:

Contributor: Robert Glen, University of Cambridge - Thu, 18 Feb 2021 21:10:32 +0000