Submission Details

LIZ-THE-60d741c6

Molecule(s):

CC(=O)C1CNC2CN(CC(N)=O)CC2C1

LIZ-THE-60d741c6-1

CC(=O)C1CNC2CN(CC(N)=O)CC2C1

Check Availability on Manifold View

Design Rationale:

By eye, linked X1412 and X0874, to combine hydrogen bonding (to protein backbone) potential of both fragments.

Inspired By:

NC(=O)[C@H]1CCC[C@H]1c1ccsc1

AAR-POS-d2a4d1df-14

O=C(CCl)N1CCN(C(=O)c2cccs2)CC1

AAR-POS-0daf6b7e-16

Discussion:

Contributor: Liz Morris, The Francis Crick Institute - Thu, 26 Mar 2020 16:03:56 +0000