Submission Details

HAN-NEW-5f56c3bc
Molecule(s):
Cc1ncncc1NC(=O)Nc1ccccc1

HAN-NEW-5f56c3bc-1

Cc1ncncc1NC(=O)Nc1ccccc1

3-aminopyridine-like Made Check Availability on Manifold View
CC(=O)NCCc1c[nH]c2c(CCNS(C)(=O)=O)cc(C)cc12

HAN-NEW-5f56c3bc-2

CC(=O)NCCc1c[nH]c2c(CCNS(C)(=O)=O)cc(C)cc12

O=C(Nc1ccccc1)Nc1cnccc1CCNC(=O)NC1CCCCC1

HAN-NEW-5f56c3bc-3
Duplicate of:
DAR-DIA-03336633-1

O=C(Nc1ccccc1)Nc1cnccc1CCNC(=O)NC1CCCCC1

Duplicate 3-aminopyridine-like Check Availability on Manifold View
CC(=O)NCCc1c[nH]c2c(CCCC3CN(C(=O)CCl)CCN3C(C)=O)cccc12

HAN-NEW-5f56c3bc-4

CC(=O)NCCc1c[nH]c2c(CCCC3CN(C(=O)CCl)CCN3C(C)=O)cccc12

piperazine-chloroacetamide Check Availability on Manifold View
CC(=O)N(CCCC(=O)N(c1ccc(C)cc1)C1C=CS(=O)(=O)C1)c1cnccc1C

HAN-NEW-5f56c3bc-5

CC(=O)N(CCCC(=O)N(c1ccc(C)cc1)C1C=CS(=O)(=O)C1)c1cnccc1C

Design Rationale:

Design carried out my eye looking at merging and linking fragments. Designs include linking of fragments 0072 with 0104; 0107 with 0434, 0434 with 0540, 1493 with 1040, 1375 with 0107

Inspired By:
Discussion:

Contributor: Hannah Stewart, Newcastle University - Fri, 20 Mar 2020 11:56:09 +0000