Submission Details
Molecule(s):
O=C(Nc1cccnc1)C1CC2CC1CN2C(=O)CCl
O=C(CCl)N1C[C@@]2(c3cccc(Cl)c3)CC1c1c(OCCN3CCOCC3)cccc12
O=C(CCl)N1CC2CC1CN2C(c1ccccc1)C(CO)CO
O=C(CCl)N1CC2CC1CN2C(c1ccccc1)C1CCCCC1
O=C(CCl)N1CC2CC1CN2C(c1ccccc1)C1CCOCC1
O=C(CCl)N1CC2CC1CN2Cc1cc(Cl)cc2cnccc12
O=C(CCl)N1CC2CC1CN2Cc1nc(-c2cccs2)no1
O=C(CCl)N1CC2CC1C(N(CC1CCCCC1)C1CCC(O)CC1)C2
O=C(CCl)N1CC2CC(c3nc(-c4cccnc4)nc4ccccc34)C1C2
O=C(c1ccc[nH]1)N1CC2CC3CN(C(=O)CCl)C2(C3)C1
O=C(CCl)N1CC2CC1CC2c1nc(-c2cccnc2)nc2ccccc12
O=C(CCl)N1CC2CC1CN2C1(c2ccccc2)CCCCC1
O=C(Nc1cc(Cl)nc2ccccc12)C1CC2CC1CN2C(=O)CCl
O=C(Nc1ccc2c(c1)[nH]c1ccccc12)C1CC2CC1CN2C(=O)CCl
O=C(Nc1c[nH]c2ccc(Br)cc12)C1CC2CC1CN2C(=O)CCl
O=C(Nc1ccc(Cl)cc1)C1CC2CC1CN2C(=O)CCl
O=C(Nc1ccc(N2CCNC2=O)cc1)C1CC2CC1CN2C(=O)CCl
O=C(Nc1cccc(C2=NN=C3CCCCC32)c1)C1CC2CC1CN2C(=O)CCl
O=C(Nc1cccc(-c2cc[nH]n2)c1)C1CC2CC1CN2C(=O)CCl
O=C(Nc1ccccc1)C1CC2CC1CN2C(=O)CCl
O=C(Nc1ccccc1Br)C1CC2CC1CN2C(=O)CCl
O=C(Nc1ccn(-c2ccccc2)n1)C1CC2CC1CN2C(=O)CCl
O=C(NCc1ccc(Cl)cc1CN1CC2CC1CN2C(=O)CCl)[C@@H]1CCCOC1
O=C1CC(C(c2ccccc2)N2CC3CC2CN3C(=O)CCl)CCN1
Design Rationale:
ordered chloroacetamides modified by adding an extra C atom above a piperidine or piperazine ring (similar to x0770 transformed into x3077)