Submission Details

Molecule(s):
C=CC(=O)N1CCNC(=O)[C@@H]1Cc1nc2ccccc2o1

DAV-IMP-59dd6621-2

C=CC(=O)N1CCNC(=O)[C@@H]1Cc1nc2ccccc2o1

CCOC(=O)/C(=C/c1cccc(OC)c1)C(=O)c1ccccc1

DAV-IMP-59dd6621-3

CCOC(=O)/C(=C/c1cccc(OC)c1)C(=O)c1ccccc1

C=CC(=O)Nc1cccc(-c2ccc3c(c2)OCCO3)n1

DAV-IMP-59dd6621-4

C=CC(=O)Nc1cccc(-c2ccc3c(c2)OCCO3)n1

C=CC(=O)NC[C@@H]1C[C@H](F)CN1c1nnc(C)o1

DAV-IMP-59dd6621-5

C=CC(=O)NC[C@@H]1C[C@H](F)CN1c1nnc(C)o1

C=CC(=O)NC1CC(OCc2ccccc2)C1(C)C

DAV-IMP-59dd6621-7

C=CC(=O)NC1CC(OCc2ccccc2)C1(C)C

C=CC(=O)N1CCCNC(=O)[C@@H]1CC(C)C

DAV-IMP-59dd6621-8

C=CC(=O)N1CCCNC(=O)[C@@H]1CC(C)C

C=CC(=O)N1CCCc2cc(C(=O)O)ccc21

DAV-IMP-59dd6621-9

C=CC(=O)N1CCCc2cc(C(=O)O)ccc21

O=C(/C=C/c1cccc([N+](=O)[O-])c1)c1ccccc1

DAV-IMP-59dd6621-10

O=C(/C=C/c1cccc([N+](=O)[O-])c1)c1ccccc1

O=C(/C=C/c1ccccc1[N+](=O)[O-])c1ccccc1

DAV-IMP-59dd6621-11

O=C(/C=C/c1ccccc1[N+](=O)[O-])c1ccccc1

C=CC(=O)N[C@H](c1nccn1C)C1CCOCC1

DAV-IMP-59dd6621-13

C=CC(=O)N[C@H](c1nccn1C)C1CCOCC1

C=CC(=O)Nc1cc(C2CC2)nn1-c1ncccn1

DAV-IMP-59dd6621-17

C=CC(=O)Nc1cc(C2CC2)nn1-c1ncccn1

C=CC(=O)N(C)[C@@H](C)c1ccccc1N1CCCS1(=O)=O

DAV-IMP-59dd6621-18

C=CC(=O)N(C)[C@@H](C)c1ccccc1N1CCCS1(=O)=O

C=CC(=O)N1CCCc2cc(C(=O)OC)ccc21

DAV-IMP-59dd6621-22

C=CC(=O)N1CCCc2cc(C(=O)OC)ccc21

C=CC(=O)N1CCN(c2ccccc2[N+](=O)[O-])CC1

DAV-IMP-59dd6621-23

C=CC(=O)N1CCN(c2ccccc2[N+](=O)[O-])CC1

C=CC(=O)N1CCN(CC)c2cc(C(=O)NCc3ccc(OC)cc3)ccc21

DAV-IMP-59dd6621-24

C=CC(=O)N1CCN(CC)c2cc(C(=O)NCc3ccc(OC)cc3)ccc21

C=CC(=O)N1CCN(C(=O)OC)c2ccccc21

DAV-IMP-59dd6621-25

C=CC(=O)N1CCN(C(=O)OC)c2ccccc21

C#CCNC(=O)N1CCN(C(=O)C=C)c2ccccc21

DAV-IMP-59dd6621-26

C#CCNC(=O)N1CCN(C(=O)C=C)c2ccccc21

C=CC(=O)N1CCCc2cc(C(=O)NCc3ccccc3)ccc21

DAV-IMP-59dd6621-27

C=CC(=O)N1CCCc2cc(C(=O)NCc3ccccc3)ccc21

C=CC(=O)N1CCN(C(=O)NCCN)c2ccccc21

DAV-IMP-59dd6621-28

C=CC(=O)N1CCN(C(=O)NCCN)c2ccccc21

C#CCNC(=O)c1ccc2c(c1)CCCN2C(=O)C=C

DAV-IMP-59dd6621-29

C#CCNC(=O)c1ccc2c(c1)CCCN2C(=O)C=C


Design Rationale:

All cmpds were hits in first round qIT screening against COVID19 3CL

Other Notes:

I've selected x0072 only because I have to select something to submit!

Inspired By:
Discussion: