Submission Details
Molecule(s):
C=CC(=O)Nc1ccc(Cl)c(C#N)c1
C=CC(=O)N1CCNC(=O)[C@@H]1Cc1nc2ccccc2o1
CCOC(=O)/C(=C/c1cccc(OC)c1)C(=O)c1ccccc1
C=CC(=O)Nc1cccc(-c2ccc3c(c2)OCCO3)n1
C=CC(=O)NC[C@@H]1C[C@H](F)CN1c1nnc(C)o1
C=CC(=O)Nc1cc(F)cc(N2CCCC2)c1
C=CC(=O)NC1CC(OCc2ccccc2)C1(C)C
C=CC(=O)N1CCCNC(=O)[C@@H]1CC(C)C
C=CC(=O)N1CCCc2cc(C(=O)O)ccc21
O=C(/C=C/c1cccc([N+](=O)[O-])c1)c1ccccc1
O=C(/C=C/c1ccccc1[N+](=O)[O-])c1ccccc1
O=C(/C=C/c1ccccc1)c1ccccc1
C=CC(=O)N[C@H](c1nccn1C)C1CCOCC1
C=CC(=O)N1CCN(C)c2ncccc21
C=CC(=O)NC1c2ccccc2CCC1n1ccnc1
C=CC(=O)NCCc1cn2c(n1)SCC2
C=CC(=O)Nc1cc(C2CC2)nn1-c1ncccn1
C=CC(=O)N(C)[C@@H](C)c1ccccc1N1CCCS1(=O)=O
C=CC(=O)N[C@H]1CCc2ncsc2C1
C=CC(=O)NCC1CN2CCCCC2CO1
C=CS(=O)(=O)NC1CCN(C(C)=O)CC1
C=CC(=O)N1CCCc2cc(C(=O)OC)ccc21
C=CC(=O)N1CCN(c2ccccc2[N+](=O)[O-])CC1
C=CC(=O)N1CCN(CC)c2cc(C(=O)NCc3ccc(OC)cc3)ccc21
C=CC(=O)N1CCN(C(=O)OC)c2ccccc21
C#CCNC(=O)N1CCN(C(=O)C=C)c2ccccc21
C=CC(=O)N1CCCc2cc(C(=O)NCc3ccccc3)ccc21
C=CC(=O)N1CCN(C(=O)NCCN)c2ccccc21
C#CCNC(=O)c1ccc2c(c1)CCCN2C(=O)C=C
C=CC(=O)N1CCCc2cc(C(N)=O)ccc21
Design Rationale:
All cmpds were hits in first round qIT screening against COVID19 3CL
Other Notes:
I've selected x0072 only because I have to select something to submit!