Submission Details

VLA-UCB-53bdeed6
Molecule(s):
O=C1C[C@@H](c2cccc(Cl)c2)C(=O)N1c1nncn1C1CC1

VLA-UCB-53bdeed6-1

O=C1C[C@@H](c2cccc(Cl)c2)C(=O)N1c1nncn1C1CC1

3-aminopyridine-like Check Availability on Manifold View
O=C(Nc1nn[nH]c1C1CC1)[C@@H]1CCOc2ccc(Cl)cc21

VLA-UCB-53bdeed6-2

O=C(Nc1nn[nH]c1C1CC1)[C@@H]1CCOc2ccc(Cl)cc21

3-aminopyridine-like Check Availability on Manifold View
O=C(Nc1cn[nH]c1C1CC1)[C@@H]1CCOc2ccc(Cl)cc21

VLA-UCB-53bdeed6-3

O=C(Nc1cn[nH]c1C1CC1)[C@@H]1CCOc2ccc(Cl)cc21

3-aminopyridine-like Ordered Check Availability on Manifold View
O=C1C[C@]2(CCOc3ccc(Cl)cc32)C(=O)N1c1nncn1C1CC1

VLA-UCB-53bdeed6-4

O=C1C[C@]2(CCOc3ccc(Cl)cc32)C(=O)N1c1nncn1C1CC1

3-aminopyridine-like Check Availability on Manifold View
O=C1C[C@]2(CCOc3ccc(Cl)cc32)C(=O)N1c1cn[nH]c1C1CC1

VLA-UCB-53bdeed6-5

O=C1C[C@]2(CCOc3ccc(Cl)cc32)C(=O)N1c1cn[nH]c1C1CC1

3-aminopyridine-like Check Availability on Manifold View
O=C1C[C@]2(CCOc3ccc(Cl)cc32)C(=O)N1c1nn[nH]c1C1CC1

VLA-UCB-53bdeed6-6

O=C1C[C@]2(CCOc3ccc(Cl)cc32)C(=O)N1c1nn[nH]c1C1CC1

3-aminopyridine-like Check Availability on Manifold View
Design Rationale:

Designs following up on JAG-UCB-a3ef7265-20

Other Notes:

Submitted by Matt of PostEra, on Vladas's behalf

Discussion:

Contributor: Vladas, UCB - Thu, 25 Jun 2020 14:50:25 +0000