Submission Details
Molecule(s):
CNc1ncc(C#N)cc1Cc1ccc2c(c1)C(=O)NC2
N#Cc1cnc(N)c(Cc2ccc3c(c2)C(=O)NC3)c1
CCNc1ncc(C#N)cc1Cc1ccc2c(c1)C(=O)NC2
CCNc1ccc(C#N)cc1Cc1ccc2c(c1)C(=O)NC2
CCNc1ncc(C#N)cc1Cc1ccc2c(c1)C(=O)CC2
CCNC1=C(Cc2ccc3c(c2)C(=O)NC3)C=C(C#N)CN1
CCNc1ncc(C#N)cc1-c1ccc2c(c1)C(=O)NC2
CCCc1ncc(C#N)cc1Cc1ccc2c(c1)C(=O)NC2
CCNc1ncc(C#N)cc1Cc1ccc2c(c1)C(=S)NC2
N#Cc1cnc(NCCl)c(Cc2ccc3c(c2)C(=O)NC3)c1
N#Cc1cnc(NCF)c(Cc2ccc3c(c2)C(=O)NC3)c1
CCNc1ncc(C#N)cc1Cc1ccc2c(c1)C(=O)[N+]C2
CCCc1ccc(C#N)cc1Cc1ccc2c(c1)C(=O)NC2
CCNc1ncc(C#[N+2])cc1Cc1ccc2c(c1)C(=O)NC2
CCNc1ncc(C#N)cc1Nc1ccc2c(c1)C(=O)NC2
CCNc1ncc(C#N)cc1Cc1ccc2c(n1)C(=O)NC2
CCNc1ncc(C#N)cc1Cc1cc2c(cn1)CNC2=O
CCNc1ncc(C#N)cc1Cc1cnc2c(c1)C(=O)NC2
CCNc1nnc(C#N)cc1Cc1ccc2c(c1)C(=O)NC2
CCNc1ncc(C#N)nc1Cc1ccc2c(c1)C(=O)NC2
CCNc1nnc(C#N)nc1Cc1ccc2c(c1)C(=O)NC2
CCNc1ncc(C#N)cc1CCc1ccc2c(c1)C(=O)NC2
CCCc1ccc(C#N)cc1Cc1ccc2c(c1)C(=O)CC2
CCNc1ccc(C#N)cc1Cc1ccc2c(c1)C(=O)CC2
CCCc1ncc(C#N)cc1Cc1ccc2c(c1)C(=O)CC2
Design Rationale:
by eye, inspired by GAB-REV-df6-19 (top active-covalent)