Submission Details

VLA-UNK-4cf5aa07
Molecule(s):
O=C(Cc1cccc(Cl)c1)Nc1snc2ccccc12

VLA-UNK-4cf5aa07-1

O=C(Cc1cccc(Cl)c1)Nc1snc2ccccc12

3-aminopyridine-like Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1onc2ccccc12

VLA-UNK-4cf5aa07-2

O=C(Cc1cccc(Cl)c1)Nc1onc2ccccc12

3-aminopyridine-like Check Availability on Manifold View
Design Rationale:

Two additional IQ replacements in one step reaction, not included in the previous enumerations. 2,1-Benzisoxazole version of JIN-POS-6dc588a4-8 might present a better h-bond acceptor to the binding pocket.

Inspired By:
Discussion:

Contributor: Vladas Oleinikovas - Sat, 03 Apr 2021 13:30:10 +0000