Submission Details

Molecule(s):
CNS(=O)(=O)Cc1ccc2[nH]cc(CCN(C)C)c2c1

ANT-OPE-47f3bb65-1
Duplicate of:
LON-WEI-b8d98729-34

CNS(=O)(=O)Cc1ccc2[nH]cc(CCN(C)C)c2c1

CN(C)CCc1c[nH]c2ccc(CS(N)(=O)=O)cc12

ANT-OPE-47f3bb65-2

CN(C)CCc1c[nH]c2ccc(CS(N)(=O)=O)cc12

CN(C)CCc1c[nH]c2ccc(CS(=O)(=O)N(C)C)cc12

ANT-OPE-47f3bb65-3

CN(C)CCc1c[nH]c2ccc(CS(=O)(=O)N(C)C)cc12

CN(C)CCc1c[nH]c2ccc(S(N)(=O)=O)cc12

ANT-OPE-47f3bb65-4

CN(C)CCc1c[nH]c2ccc(S(N)(=O)=O)cc12

CN(C)CCc1c[nH]c2ccc(S(=O)(=O)N(C)C)cc12

ANT-OPE-47f3bb65-5

CN(C)CCc1c[nH]c2ccc(S(=O)(=O)N(C)C)cc12


Design Rationale:

Sumatriptan is already approved in UK and US - has some similarity to fragment #104

Inspired By:
Discussion: