Submission Details

JOH-MSK-46727e7b
Molecule(s):
CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](CC1CCNC1=O)C(O)S(=O)(=O)O

JOH-MSK-46727e7b-1

CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](CC1CCNC1=O)C(O)S(=O)(=O)O

Design Rationale:

GC376: Prodrug form of feline coronavirus inhibitor claimed to inhibit SARS-CoV-2 Mpro. Sodium salt form.

Other Notes:

See https://www.nature.com/articles/s41467-020-18096-2

Discussion:

Contributor: John Chodera, MSK - Fri, 28 Aug 2020 16:45:12 +0000