Submission Details

Molecule(s):
NS(=O)(=O)CCNc1ncccc1CN1CCN(C(=O)CCl)CC1

STU-CHA-464c0256-1

NS(=O)(=O)CCNc1ncccc1CN1CCN(C(=O)CCl)CC1

piperazine-chloroacetamide Ordered Check Availability on Manifold View

Design Rationale:

Modification of covalent fragment x0692 and x0305. Not docked in to crystal structure. Modest docking score for parent N-Et amine-pyridine. Looking for sulfonamide to make interactions with Glu166 or Gln189

Inspired By:
Discussion: