Submission Details

EDJ-MED-40e596c8
Molecule(s):
CNS(=O)(=O)CN1Cc2ccc(Cl)cc2C2(CCN(c3cncc4ccccc34)C2=O)C1

EDJ-MED-40e596c8-1

CNS(=O)(=O)CN1Cc2ccc(Cl)cc2C2(CCN(c3cncc4ccccc34)C2=O)C1

3-aminopyridine-like Ordered Check Availability on Manifold View
O=C1N(c2cncc3ccccc23)CCC12CN(CS(=O)(=O)NCC1CC1)Cc1ccc(Cl)cc12

EDJ-MED-40e596c8-2

O=C1N(c2cncc3ccccc23)CCC12CN(CS(=O)(=O)NCC1CC1)Cc1ccc(Cl)cc12

3-aminopyridine-like Ordered Check Availability on Manifold View
O=C(NCCN1Cc2ccc(Cl)cc2C2(CCN(c3cncc4ccccc34)C2=O)C1)C1CC1

EDJ-MED-40e596c8-3

O=C(NCCN1Cc2ccc(Cl)cc2C2(CCN(c3cncc4ccccc34)C2=O)C1)C1CC1

3-aminopyridine-like Check Availability on Manifold View
O=C(NCCN1CC2(CCN(c3cncc4ccccc34)C2=O)c2cc(Cl)ccc2C1=O)C1CC1

EDJ-MED-40e596c8-4

O=C(NCCN1CC2(CCN(c3cncc4ccccc34)C2=O)c2cc(Cl)ccc2C1=O)C1CC1

3-aminopyridine-like Check Availability on Manifold View
O=C1c2ccc(Cl)cc2C2(CCN(c3cncc4ccccc34)C2=O)CN1CS(=O)(=O)NCC1CC1

EDJ-MED-40e596c8-5

O=C1c2ccc(Cl)cc2C2(CCN(c3cncc4ccccc34)C2=O)CN1CS(=O)(=O)NCC1CC1

3-aminopyridine-like Ordered Check Availability on Manifold View
Design Rationale:

Analogs to MAT-POS-c7726e07-5

Inspired By:
Discussion:

Contributor: Ed J Griffen, MedChemica Consultancy Ltd - Fri, 21 Jan 2022 15:05:52 +0000