Submission Details

DAV-CRI-3fe943ba
Molecule(s):
NS(=O)(=O)C1CCc2ccc(C3CN(C(=O)CCl)Cc4ccccc43)cc2C1

DAV-CRI-3fe943ba-1

NS(=O)(=O)C1CCc2ccc(C3CN(C(=O)CCl)Cc4ccccc43)cc2C1

NS(=O)(=O)C1CCc2cc(C3CN(C(=O)CCl)Cc4ccccc43)ccc2C1

DAV-CRI-3fe943ba-2

NS(=O)(=O)C1CCc2cc(C3CN(C(=O)CCl)Cc4ccccc43)ccc2C1

Design Rationale:

By linking of X0161 and X1392 with some variants. Retains covalent warhead.

Inspired By:
Discussion:

Contributor: David Briggs, Crick Institute - Thu, 26 Mar 2020 12:35:35 +0000