Submission Details

Molecule(s):
CC(NC(=O)CCl)c1cc(O)cc(Cl)c1

DAV-CRI-3edb475e-2

CC(NC(=O)CCl)c1cc(O)cc(Cl)c1

O=C(CCl)NC(CO)c1cccc(Cl)c1

DAV-CRI-3edb475e-4

O=C(CCl)NC(CO)c1cccc(Cl)c1

CN(C)CC(NC(=O)CCl)c1cccc(Cl)c1

DAV-CRI-3edb475e-5

CN(C)CC(NC(=O)CCl)c1cccc(Cl)c1

CC(NC(=O)CCl)c1cc(F)cc(Cl)c1

DAV-CRI-3edb475e-6

CC(NC(=O)CCl)c1cc(F)cc(Cl)c1


Design Rationale:

Modifications of x1382, the best occupancy, high confidence covalent binder.

Inspired By:
Discussion: