Submission Details
Molecule(s):
CC(NC(=O)CCl)c1ccc(O)c(Cl)c1
CC(NC(=O)CCl)c1cc(O)cc(Cl)c1
CC(NC(=O)CCl)c1cc(Cl)ccc1O
O=C(CCl)NC(CO)c1cccc(Cl)c1
CN(C)CC(NC(=O)CCl)c1cccc(Cl)c1
CC(NC(=O)CCl)c1cc(F)cc(Cl)c1
Design Rationale:
Modifications of x1382, the best occupancy, high confidence covalent binder.