Submission Details

DAN-MCD-3ec20f87
Molecule(s):
O=C(CCl)N1CCN(S(=O)(=O)c2ccsc2)[C@H](C(=O)N2CCOCC2)C1

DAN-MCD-3ec20f87-1

O=C(CCl)N1CCN(S(=O)(=O)c2ccsc2)[C@H](C(=O)N2CCOCC2)C1

piperazine-chloroacetamide Assayed Check Availability on Manifold View
Design Rationale:

The inspired compound below is incorporated in the core of this molecule. Crystallography data indicates that designing compounds that build from the piperazine ring will connect with the pocket that several compounds in the 3-aminopyridine like series are bound (fragment linking).

Inspired By:
Discussion:

Contributor: Dana Ferraris, McDaniel College - Fri, 20 Aug 2021 16:34:14 +0000