Submission Details

PEI-IMP-3d837503
Molecule(s):
CCOC(=O)/C=C/N1CCN(S(=O)(=O)c2ccccc2)CC1

PEI-IMP-3d837503-1

CCOC(=O)/C=C/N1CCN(S(=O)(=O)c2ccccc2)CC1

C=CC(=O)N1CCN(S(=O)(=O)c2ccccc2)CC1

PEI-IMP-3d837503-2

C=CC(=O)N1CCN(S(=O)(=O)c2ccccc2)CC1

C=CS(=O)(=O)N1CCN(S(=O)(=O)c2ccccc2)CC1

PEI-IMP-3d837503-3

C=CS(=O)(=O)N1CCN(S(=O)(=O)c2ccccc2)CC1

C#CC(=O)N1CCN(S(=O)(=O)c2ccccc2)CC1

PEI-IMP-3d837503-4

C#CC(=O)N1CCN(S(=O)(=O)c2ccccc2)CC1

O=S(=O)(c1ccccc1)N1CCN(CC2CO2)CC1

PEI-IMP-3d837503-5

O=S(=O)(c1ccccc1)N1CCN(CC2CO2)CC1

Design Rationale:

Covalent warhead replacement

Inspired By:
Discussion:

Contributor: Peihao Zhao, Imperial College London - Wed, 14 Jul 2021 00:02:30 +0000