Submission Details

MAT-POS-3b92565d
Molecule(s):
COc1ccc(Cl)cc1CC(=O)Nc1cncc2ccccc12

MAT-POS-3b92565d-1

COc1ccc(Cl)cc1CC(=O)Nc1cncc2ccccc12

3-aminopyridine-like Assayed Check Availability on Manifold View
COc1cc(Cl)cc(CC(=O)Nc2cncc3ccccc23)c1

MAT-POS-3b92565d-2
Duplicate of:
ALP-POS-3b848b35-1

COc1cc(Cl)cc(CC(=O)Nc2cncc3ccccc23)c1

Duplicate 3-aminopyridine-like Check Availability on Manifold View
O=C(Cc1cc(Cl)cc(OC2CC(=O)N2)c1)Nc1cncc2ccccc12

MAT-POS-3b92565d-3
Duplicate of:
ALP-POS-3b848b35-2

O=C(Cc1cc(Cl)cc(OC2CC(=O)N2)c1)Nc1cncc2ccccc12

Duplicate 3-aminopyridine-like Assayed Check Availability on Manifold View
COc1ccc(Cl)cc1CC(=O)Nc1cc(=O)[nH]c2ccccc12

MAT-POS-3b92565d-4
Duplicate of:
MAT-POS-e1b5ac6b-2

COc1ccc(Cl)cc1CC(=O)Nc1cc(=O)[nH]c2ccccc12

Duplicate 3-aminopyridine-like Check Availability on Manifold View
COc1cc(Cl)cc(CC(=O)Nc2cc(=O)[nH]c3ccccc23)c1

MAT-POS-3b92565d-5

COc1cc(Cl)cc(CC(=O)Nc2cc(=O)[nH]c3ccccc23)c1

3-aminopyridine-like Check Availability on Manifold View
O=C(Cc1cc(Cl)cc(OC2CC(=O)N2)c1)Nc1cc(=O)[nH]c2ccccc12

MAT-POS-3b92565d-6

O=C(Cc1cc(Cl)cc(OC2CC(=O)N2)c1)Nc1cc(=O)[nH]c2ccccc12

3-aminopyridine-like Assayed Check Availability on Manifold View
COc1ccc(Cl)cc1CC(=O)Nc1cn(C)c(=O)c2ccccc12

MAT-POS-3b92565d-7

COc1ccc(Cl)cc1CC(=O)Nc1cn(C)c(=O)c2ccccc12

3-aminopyridine-like Check Availability on Manifold View
COc1cc(Cl)cc(CC(=O)Nc2cn(C)c(=O)c3ccccc23)c1

MAT-POS-3b92565d-8

COc1cc(Cl)cc(CC(=O)Nc2cn(C)c(=O)c3ccccc23)c1

3-aminopyridine-like Check Availability on Manifold View
Cn1cc(NC(=O)Cc2cc(Cl)cc(OC3CC(=O)N3)c2)c2ccccc2c1=O

MAT-POS-3b92565d-9

Cn1cc(NC(=O)Cc2cc(Cl)cc(OC3CC(=O)N3)c2)c2ccccc2c1=O

3-aminopyridine-like Check Availability on Manifold View
COc1ccc(Cl)cc1CC(=O)Nn1cnc2ccccc21

MAT-POS-3b92565d-10

COc1ccc(Cl)cc1CC(=O)Nn1cnc2ccccc21

3-aminopyridine-like Check Availability on Manifold View
COc1cc(Cl)cc(CC(=O)Nn2cnc3ccccc32)c1

MAT-POS-3b92565d-11

COc1cc(Cl)cc(CC(=O)Nn2cnc3ccccc32)c1

3-aminopyridine-like Check Availability on Manifold View
O=C1CC(Oc2cc(Cl)cc(CC(=O)Nn3cnc4ccccc43)c2)N1

MAT-POS-3b92565d-12
Duplicate of:
MAT-POS-c478e61b-1

O=C1CC(Oc2cc(Cl)cc(CC(=O)Nn3cnc4ccccc43)c2)N1

Duplicate 3-aminopyridine-like Assayed Check Availability on Manifold View
O=C(Cn1nnc2ccccc21)NCc1cccc(Cl)c1

MAT-POS-3b92565d-13

O=C(Cn1nnc2ccccc21)NCc1cccc(Cl)c1

O=C(Cn1nnc2ccccc21)Nc1cccc(Cl)c1

MAT-POS-3b92565d-14
Duplicate of:
BEN-DND-61647d40-12

O=C(Cn1nnc2ccccc21)Nc1cccc(Cl)c1

Duplicate 3-aminopyridine-like Assayed Check Availability on Manifold View
Design Rationale:

Easy to make molecules from Enamine building blocks that probe the p1-p2 site binders.

Inspired By:
Discussion:

Contributor: Matt Robinson, PostEra - Thu, 23 Jul 2020 21:36:05 +0000