Submission Details

NIM-UNI-363644a0
Molecule(s):
NS(=O)(=O)c1ccc2cccc(CN3CCN(C(=O)CCl)C(c4cccnc4)C3)c2c1

NIM-UNI-363644a0-1

NS(=O)(=O)c1ccc2cccc(CN3CCN(C(=O)CCl)C(c4cccnc4)C3)c2c1

piperazine-chloroacetamide Ordered Check Availability on Manifold View
NS(=O)(=O)c1ccc2cccc(CN3CCN(C(=O)CCl)C(c4cnccc4CCNC(=O)NC4CCCCC4)C3)c2c1

NIM-UNI-363644a0-2

NS(=O)(=O)c1ccc2cccc(CN3CCN(C(=O)CCl)C(c4cnccc4CCNC(=O)NC4CCCCC4)C3)c2c1

Design Rationale:

Combining fragments x0770 and x0946, and the key pyridine seen in x0426, x0434 and many other fragments.

Other Notes:

Fragalysis Snapshot: https://fragalysis.diamond.ac.uk/viewer/react/snapshot/95a6097f-7be1-4ad1-808c-b959f06f6929

Inspired By:
Discussion:

Contributor: Nimesh Mistry, University of Leeds - Thu, 02 Apr 2020 06:37:27 +0000