Submission Details

Molecule(s):
COc1ccc2[nH]cc(CCNC(C)=O)c2c1

JOH-MSK-35a8745a-1

COc1ccc2[nH]cc(CCNC(C)=O)c2c1


Design Rationale:

Melatonin, an endogenous molecule that has low peak concentrations in high-risk COVID-19 patients but high peak concentrations in low-risk COVID-19 patients

Other Notes:

Suggested by Martin Smiesko and Markus Lill who noted that Diamond hit x0104 was remarkably similar to melatonin (with -F instead of -OMe substituent on indole ring)

Inspired By:
Discussion: