Submission Details

Molecule(s):
O=C(Oc1cncc(Cl)c1)c1cccc2[nH]ccc12

NAU-LAT-356bd3c2-1
Duplicate of:
ALP-POS-c59291d4-5

O=C(Oc1cncc(Cl)c1)c1cccc2[nH]ccc12

Duplicate activated-ester Assayed Check Availability on Manifold View
O=C(Nc1cncc(Cl)c1)c1cccc2[nH]ccc12

NAU-LAT-356bd3c2-2

O=C(Nc1cncc(Cl)c1)c1cccc2[nH]ccc12

CN(C(=O)c1cccc2[nH]ccc12)c1cncc(Cl)c1

NAU-LAT-356bd3c2-3

CN(C(=O)c1cccc2[nH]ccc12)c1cncc(Cl)c1

Cn1ccc2c(C(=O)Oc3cncc(Cl)c3)cccc21

NAU-LAT-356bd3c2-4

Cn1ccc2c(C(=O)Oc3cncc(Cl)c3)cccc21

O=C(Oc1cncc(Cl)c1)c1cccc2occc12

NAU-LAT-356bd3c2-5

O=C(Oc1cncc(Cl)c1)c1cccc2occc12

O=C(Oc1cncc(Cl)c1)c1cccc2c1CCN2

NAU-LAT-356bd3c2-6

O=C(Oc1cncc(Cl)c1)c1cccc2c1CCN2

O=C(Oc1cncc2ccccc12)c1cccc2[nH]ccc12

NAU-LAT-356bd3c2-7

O=C(Oc1cncc2ccccc12)c1cccc2[nH]ccc12

O=C(Nc1ncnn1C1CC1)c1cccc2[nH]ccc12

NAU-LAT-356bd3c2-8

O=C(Nc1ncnn1C1CC1)c1cccc2[nH]ccc12

O=C(Oc1cncc(Cl)c1)c1cccc2[nH]c(Cl)cc12

NAU-LAT-356bd3c2-9

O=C(Oc1cncc(Cl)c1)c1cccc2[nH]c(Cl)cc12

O=C(Oc1cncc(Cl)c1)c1cccc2[nH]ncc12

NAU-LAT-356bd3c2-10

O=C(Oc1cncc(Cl)c1)c1cccc2[nH]ncc12

O=C(Oc1cncc(Cl)c1)c1cccc2[nH]cnc12

NAU-LAT-356bd3c2-11

O=C(Oc1cncc(Cl)c1)c1cccc2[nH]cnc12

O=C1Cc2c(cccc2C(=O)Oc2cncc(Cl)c2)N1

NAU-LAT-356bd3c2-12

O=C1Cc2c(cccc2C(=O)Oc2cncc(Cl)c2)N1

O=C1Nc2cccc(C(=O)Oc3cncc(Cl)c3)c2C1=O

NAU-LAT-356bd3c2-13

O=C1Nc2cccc(C(=O)Oc3cncc(Cl)c3)c2C1=O


Design Rationale:

Short SAR proposed on active compound ALP-POS-c59291d4-5.

Inspired By:
Discussion: