Submission Details
Molecule(s):
O=C(C1CCN(c2ccncc2)CC1)N1CCCCC1
O=C(C1CCN(c2ccncc2)CC1)N1CCOCC1
O=C(C1CCN(c2ccncc2)CC1)N1CCS(=O)(=O)CC1
O=C(C1CCCN(c2ccncc2)C1)N1CCCCC1
O=C(C1CCCN(c2ccncc2)C1)N1CCOCC1
O=C(C1CCCN(c2ccncc2)C1)N1CCS(=O)(=O)CC1
Design Rationale:
N-pyridyl-isonipecotamides and nipecotamides as main template that could reproduce lenght and orientation of the selected fragment of reference. No structural alert of toxicity.
Other Notes:
Two step synthesis without need of protective groups