Submission Details

Molecule(s):
O=C(O)CCC(=O)N1CCN(S(=O)(=O)c2cc(F)cc(F)c2)CC1

ZAC-MCD-2bc172dc-1

O=C(O)CCC(=O)N1CCN(S(=O)(=O)c2cc(F)cc(F)c2)CC1


Design Rationale:

I added the carbon chain with the carboxylic acid to possibly add some hydrogen bonding with a histidine in a back pocket, and the Fluorine to possibly help with the selectivity.

Inspired By:
Discussion: