Submission Details
Molecule(s):
CCOc1ccc(/C=C/C(=O)c2cc(Cl)cc(Br)c2O)cc1
CCOc1ccc(/C=C/C(=O)c2cc(C)cc(Br)c2O)cc1
CCOc1ccc(/C=C/C(=O)c2cc(Cl)cc(I)c2O)cc1
CCOc1ccc(/C=C/C(=O)c2cc(C)cc(I)c2O)cc1
CCOc1ccc(/C=C/C(=O)c2cc(I)cc(I)c2O)cc1
CCOc1ccccc1/C=C/C(=O)c1cc(Cl)cc(Br)c1O
CCOc1ccccc1/C=C/C(=O)c1cc(C)cc(Br)c1O
CCOc1ccccc1/C=C/C(=O)c1cc(Cl)cc(I)c1O
CCOc1ccccc1/C=C/C(=O)c1cc(C)cc(I)c1O
CCOc1ccccc1/C=C/C(=O)c1cc(I)cc(I)c1O
Design Rationale:
The differently substituted chalcone derivatives are binding with coronavirus protein in the primary investigation done by molecular docking screenings.
Other Notes:
The synthesis of these derivatives of chalones is very very simple and affordable if you want to know the details please feel free to contact me +91 8007840827 or mail me on ravidule@gmial.com