Submission Details

EDJ-MED-28cccd0c
Molecule(s):
O=C(Nc1cncc2ccccc12)C1CN(S(=O)(=O)CC2CCOCC2)Cc2ccccc21

EDJ-MED-28cccd0c-1

O=C(Nc1cncc2ccccc12)C1CN(S(=O)(=O)CC2CCOCC2)Cc2ccccc21

3-aminopyridine-like Check Availability on Manifold View
CC(C)(CS(=O)(=O)N1Cc2ccccc2C(C(=O)Nc2cncc3ccccc23)C1)S(C)(=O)=O

EDJ-MED-28cccd0c-2

CC(C)(CS(=O)(=O)N1Cc2ccccc2C(C(=O)Nc2cncc3ccccc23)C1)S(C)(=O)=O

3-aminopyridine-like Check Availability on Manifold View
CC1(CS(=O)(=O)N2Cc3ccccc3C(C(=O)Nc3cncc4ccccc34)C2)CS(=O)(=O)C1

EDJ-MED-28cccd0c-3

CC1(CS(=O)(=O)N2Cc3ccccc3C(C(=O)Nc3cncc4ccccc34)C2)CS(=O)(=O)C1

3-aminopyridine-like Check Availability on Manifold View
O=C(Nc1cncc2ccccc12)C1CN(S(=O)(=O)CC2CS(=O)(=O)C2)Cc2ccccc21

EDJ-MED-28cccd0c-4

O=C(Nc1cncc2ccccc12)C1CN(S(=O)(=O)CC2CS(=O)(=O)C2)Cc2ccccc21

3-aminopyridine-like Check Availability on Manifold View
Design Rationale:

Analogues of MAT-POS-dc2604c4-1 to explore sulfonyl chloride requirement for increased stability using high availability Enamine reagents with logP ~< MAT-POS-dc2604c4-1.

Inspired By:
Discussion:

Contributor: Ed J Griffen, MedChemica Ltd - Sun, 04 Jul 2021 17:18:08 +0000