Submission Details
Molecule(s):
O=C(CCl)N1CCN(S(=O)(=O)c2cccc(F)c2)c2cnc(NCN(c3ccccc3)C(O)NC3CCCNC3)cc21
Design Rationale:
I decided to link these two compounds together here because these two regions seemed to be in close proximity to each other in the binding pocket. I kept the 6-membered ring with a nitrogen to try to fill even more of the pocket, and then connected that with simple single bonds, and threw another amine in their to help with polarity.