Submission Details

Molecule(s):
CC1(C(=O)Nc2cncc3ccccc23)CNS(=O)(=O)c2ccc(Cl)cc21

ALP-POS-1cbc2fae-1

CC1(C(=O)Nc2cncc3ccccc23)CNS(=O)(=O)c2ccc(Cl)cc21

3-aminopyridine-like Assayed Check Availability on Manifold View
CCC1(C(=O)Nc2cncc3ccccc23)CNS(=O)(=O)c2ccc(Cl)cc21

ALP-POS-1cbc2fae-2

CCC1(C(=O)Nc2cncc3ccccc23)CNS(=O)(=O)c2ccc(Cl)cc21

3-aminopyridine-like Assayed Check Availability on Manifold View

Design Rationale:

Adding Me and Et to the quaternary carbon in the sulphonamide designs, as suggested by Ben P. in the design meeting on 24/06/2021.

Discussion: