Submission Details
Molecule(s):
O=C(CCl)N1Cc2ccccc2C(c2ccccc2)C1Cc1cccnc1
O=C(CCl)N1Cc2ccccc2C(c2ccccc2)C1Nc1cccnc1
O=C(CCl)N1Cc2ccccc2C(c2ccccc2)C1C#Cc1cccnc1
O=C(CCl)N1Cc2ccccc2C(c2cccc(Cl)c2)C1Cc1cccnc1
Cc1ccccc1C1c2ccccc2CN(C(=O)CCl)C1Cc1cccnc1
O=C(Nc1cccnc1)C1C(c2ccccc2)c2ccccc2CN1C(=O)CCl
O=C(Nc1ccncc1)C1C(c2ccccc2)c2ccccc2CN1C(=O)CCl
O=C(CCl)N1Cc2ccccc2C(c2ccc(F)cc2)C1Cc1cccnc1
Design Rationale:
by eye linking of x1392 and x0434, retaining covalent warhead, with variants.