Submission Details
Molecule(s):
O=C(Cn1ccnc1[N+](=O)[O-])NCc1ccccc1
COc1ccc(NC(=O)c2ccc(C(=N)N(C)C)cc2)c(C(=O)Nc2ccc(Cl)cn2)c1
Nc1cc(C(F)(F)F)c(-c2nc(N3CCOCC3)nc(N3CCOCC3)n2)cn1
C[C@@H]1COCCN1c1cc(C2([S@](C)(=N)=O)CC2)nc(-c2cncc3[nH]ccc23)n1
C[C@@H](Cn1ccc(-c2ccc(C#N)c(Cl)c2)n1)NC(=O)c1cc([C@@H](C)O)[nH]n1
COc1cc(OC)nc(O[C@H](C(=O)O)C(OC)(c2ccccc2)c2ccccc2)n1
O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12)N1CC[C@H](O)C1
CC(C)CCC(=O)C[C@H]1c2ccccc2C(=O)N1c1ccc2ccc(Cl)nc2n1
O=C(N[C@@H](Cc1cc(=O)[nH]c2ccccc12)C(=O)O)c1ccc(Cl)cc1
CN(C)C(=O)c1cc2cnc(Nc3ccc(N4CCNCC4)cn3)nc2n1C1CCCC1
CC1(C)CN(C(=O)c2ccc(-c3cccc4nc(NC(=O)C5CC5)nn34)cc2)C1
CC(=O)/C(C#N)=C(\O)Nc1ccc(C(F)(F)F)cc1
O=C(O)CNC(=O)c1ncc(-c2cccc(Cl)c2)cc1O
Cc1cc(Cn2nnc3c(-c4ccco4)nc(N)nc32)ccc1N
CCn1c(=O)c(-c2cc[nH]n2)cc2c(C)nc(N)nc21
NC(=O)C[S@@+]([O-])C(c1ccccc1)c1ccccc1
O=C(OCC(O)CO)c1ccccc1Nc1ccnc2cc(Cl)ccc12
C[C@@H]1CC[C@@H](c2ccoc2)N2C1CC[C@@]1(CS[C@@]3(CC[C@H]4[C@H](C)CC[C@@H](c5ccoc5)N4[C@@H]3O)C1)[C@@H]2O
Design Rationale:
The first 17 are from a repurposing campaign initiated by a computational chemistry team in Israel. The 18th is a natural product thought to be interesting