Submission Details

Molecule(s):
CN(C)c1ccc(N(C(=O)Nc2cncc3ccccc23)c2cccc(Cl)c2)cc1

FRA-DIA-13af2da5-1
Duplicate of:
MIC-UNK-d36ab305-5

CN(C)c1ccc(N(C(=O)Nc2cncc3ccccc23)c2cccc(Cl)c2)cc1

Duplicate 3-aminopyridine-like Check Availability on Manifold View
CN(C)c1ccc([C@@]2(C(=O)Nc3cncc4ccccc34)CCOc3ccc(Cl)cc32)cc1

FRA-DIA-13af2da5-2

CN(C)c1ccc([C@@]2(C(=O)Nc3cncc4ccccc34)CCOc3ccc(Cl)cc32)cc1

3-aminopyridine-like Check Availability on Manifold View

Design Rationale:

Attaching the P1' group of (280nM) PET-UNK-1901c25b-1 (dimethylaniline?) to both (140nM) MAT-POS-b3e365b9-2 (stereochemistry fixed!) and (260nM) EDJ-MED-c314995a-1. Mainly so I can see how greasy they are - because each of the inspirations are super greasy.

Other Notes:

No idea if they're easy to make...

Inspired By:
Discussion: