Submission Details

JIA-UNI-12b1f9ae
Molecule(s):
O=C(Nc1cccnc1)Nc1ccccc1CS(=O)(=O)F

JIA-UNI-12b1f9ae-1

O=C(Nc1cccnc1)Nc1ccccc1CS(=O)(=O)F

3-aminopyridine-like Check Availability on Manifold View
O=C(Nc1ccccc1CS(=O)(=O)F)NC(Cc1cccnc1)C(=O)CCl

JIA-UNI-12b1f9ae-2

O=C(Nc1ccccc1CS(=O)(=O)F)NC(Cc1cccnc1)C(=O)CCl

Design Rationale:

targeting the nucleophile, S1 specificity pocket and general base; utilizing the new click chemistry for synthesis

Inspired By:
Discussion:

Contributor: Jiang Yin, University of Alberta - Mon, 30 Mar 2020 08:09:32 +0000