Submission Details
Molecule(s):
O=C(CCl)C1NCN(S(=O)(=O)C2CCCCC2F)CC1=O
Design Rationale:
By eye. Modification of X_0769 to add hydrogen bond donors/acceptors to interact with M/C C=O of T26 S/C of H41
Other Notes:
I have some experience of structure-based drug-design of kinase inhibitors in an academic setting.