Submission Details

ALF-EVA-0e90125c
Molecule(s):
O=C(Nc1cncc2ccccc12)C1CN(C(=O)C2CCCN2)Cc2ccc(Cl)cc21

ALF-EVA-0e90125c-1

O=C(Nc1cncc2ccccc12)C1CN(C(=O)C2CCCN2)Cc2ccc(Cl)cc21

3-aminopyridine-like Check Availability on Manifold View
CN1CCCC1C(=O)N1Cc2ccc(Cl)cc2C(C(=O)Nc2cncc3ccccc23)C1

ALF-EVA-0e90125c-2

CN1CCCC1C(=O)N1Cc2ccc(Cl)cc2C(C(=O)Nc2cncc3ccccc23)C1

3-aminopyridine-like Check Availability on Manifold View
O=C1CC(S(=O)(=O)N2Cc3ccc(Cl)cc3C(C(=O)Nc3cncc4ccccc34)C2)CN1

ALF-EVA-0e90125c-3

O=C1CC(S(=O)(=O)N2Cc3ccc(Cl)cc3C(C(=O)Nc3cncc4ccccc34)C2)CN1

3-aminopyridine-like Check Availability on Manifold View
CN(C)CCS(=O)(=O)N1Cc2ccc(Cl)cc2C(C(=O)Nc2cncc3ccccc23)C1

ALF-EVA-0e90125c-4

CN(C)CCS(=O)(=O)N1Cc2ccc(Cl)cc2C(C(=O)Nc2cncc3ccccc23)C1

3-aminopyridine-like Check Availability on Manifold View
O=C(Nc1cncc2ccccc12)C1CN(S(=O)(=O)c2cnco2)Cc2ccc(Cl)cc21

ALF-EVA-0e90125c-5

O=C(Nc1cncc2ccccc12)C1CN(S(=O)(=O)c2cnco2)Cc2ccc(Cl)cc21

3-aminopyridine-like Check Availability on Manifold View
O=C(Nc1cncc2ccccc12)C1CN(S(=O)(=O)Cc2nnco2)Cc2ccc(Cl)cc21

ALF-EVA-0e90125c-6

O=C(Nc1cncc2ccccc12)C1CN(S(=O)(=O)Cc2nnco2)Cc2ccc(Cl)cc21

3-aminopyridine-like Check Availability on Manifold View
O=C(Nc1cncc2ccccc12)C1CN(S(=O)(=O)Cc2nnc[nH]2)Cc2ccc(Cl)cc21

ALF-EVA-0e90125c-7

O=C(Nc1cncc2ccccc12)C1CN(S(=O)(=O)Cc2nnc[nH]2)Cc2ccc(Cl)cc21

3-aminopyridine-like Check Availability on Manifold View
O=C(Nc1cncc2ccccc12)C1CN(S(=O)(=O)c2cocn2)Cc2ccc(Cl)cc21

ALF-EVA-0e90125c-8

O=C(Nc1cncc2ccccc12)C1CN(S(=O)(=O)c2cocn2)Cc2ccc(Cl)cc21

3-aminopyridine-like Check Availability on Manifold View
O=C(Nc1cncc2ccccc12)C1CN(Cc2ccon2)Cc2ccc(Cl)cc21

ALF-EVA-0e90125c-9

O=C(Nc1cncc2ccccc12)C1CN(Cc2ccon2)Cc2ccc(Cl)cc21

3-aminopyridine-like Check Availability on Manifold View
Design Rationale:

Designed using Evariste's proprietary design platform Frobenius. Coupled NH core to in stock aldehydes and carboxylic acids from Enamine, and (possibly not in stock but still commerically available) sulfonyl chlorides from chemspace.

Inspired By:
Discussion:

Contributor: Alfie Brennan, Evariste Technologies - Mon, 14 Jun 2021 15:11:46 +0000