Submission Details
Molecule(s):
N#Cc1cccc(C(=O)Nc2ncc([N+](=O)[O-])s2)c1
Design Rationale:
Compound is an analogue of nitazoxanide, a broad spectrum amtimicrobial drug. Nitazoxanide has been tested agains COVID2019 and showed potency in the low micromolar range EC50= 2.12 microMolar. I think it is a good lead
Other Notes:
This compound and some other related are prepared in a one step route in my medchem lab. we designed these molecules as antiprotozoal drugs, but some of them also showed antiviral effect against rotavirus and influenza