Submission Details

JOH-UNI-06d7cc04

Molecule(s):

CNC(=O)CN1CC(F)(C(=O)Nc2cncc3cc(F)ccc23)c2cc(Cl)ccc2C1=O

JOH-UNI-06d7cc04-1

CNC(=O)CN1CC(F)(C(=O)Nc2cncc3cc(F)ccc23)c2cc(Cl)ccc2C1=O

Ugi Check Availability on Manifold View

Design Rationale:

F can block racemisation AND mask the NH HBD and reduce efflux? One example shown.

Discussion:

Contributor: John Spencer, University of Sussex - Sun, 03 Oct 2021 19:38:48 +0000