Submission Details

Molecule(s):
Cc1ccncc1NC(=O)Cc1ccc2[nH]ccc2c1

VLA-UCB-00f2c2b3-1

Cc1ccncc1NC(=O)Cc1ccc2[nH]ccc2c1

3-aminopyridine-like Made Check Availability on Manifold View
Cc1ccncc1NC(=O)Cc1ccc2[nH]ncc2c1

VLA-UCB-00f2c2b3-2

Cc1ccncc1NC(=O)Cc1ccc2[nH]ncc2c1

3-aminopyridine-like Assayed Check Availability on Manifold View
Cc1ccncc1N1CC(OCCc2ncnc3[nH]nnc23)C(c2cccc(Cl)c2)C1=O

VLA-UCB-00f2c2b3-3

Cc1ccncc1N1CC(OCCc2ncnc3[nH]nnc23)C(c2cccc(Cl)c2)C1=O

3-aminopyridine-like Check Availability on Manifold View
Cc1ccncc1N1CC(OCCc2ncnc3[nH]ccc23)C(c2cccc(Cl)c2)C1=O

VLA-UCB-00f2c2b3-4

Cc1ccncc1N1CC(OCCc2ncnc3[nH]ccc23)C(c2cccc(Cl)c2)C1=O

3-aminopyridine-like Check Availability on Manifold View
Cc1ccncc1N1C(=O)C=C(c2cccc(Cl)c2)C1=O

VLA-UCB-00f2c2b3-5

Cc1ccncc1N1C(=O)C=C(c2cccc(Cl)c2)C1=O

3-aminopyridine-like Check Availability on Manifold View
Cc1ccncc1N1C(=O)Cc2ccc(NC(=O)c3ncnc4[nH]ccc34)cc21

VLA-UCB-00f2c2b3-6

Cc1ccncc1N1C(=O)Cc2ccc(NC(=O)c3ncnc4[nH]ccc34)cc21

3-aminopyridine-like Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1cccc2[nH]ncc12

VLA-UCB-00f2c2b3-7

O=C(Cc1cccc(Cl)c1)Nc1cccc2[nH]ncc12

3-aminopyridine-like Assayed Check Availability on Manifold View

Design Rationale:

Designs submitted by UCB chemists

Discussion: