Submission Details

EDJ-MED-00c1612e
Molecule(s):
COc1ccc2cncc(NC(=O)Cc3cccc(Cl)c3)c2c1

EDJ-MED-00c1612e-1

COc1ccc2cncc(NC(=O)Cc3cccc(Cl)c3)c2c1

3-aminopyridine-like Assayed Check Availability on Manifold View
Design Rationale:

Increase hydrogen bond acceptor strength of isoquinoline by 6 methoxy cf methoxy groups in kinase quinazoline inhibitors

Discussion:

Contributor: Ed J Griffen, MedChemica Ltd - Mon, 20 Jul 2020 22:06:02 +0000