Submission Details

Molecule(s):
CN(Cc1nnc2ccccn12)C(=O)c1ccnc2ccccc12

WIL-UNI-2a57d06c-1
Duplicate of:
WIL-UNI-d4749f31-7

CN(Cc1nnc2ccccn12)C(=O)c1ccnc2ccccc12

Cc1csc2ncc(C(=O)Nc3cccc4ncccc34)c(=O)n12

WIL-UNI-2a57d06c-2
Duplicate of:
WIL-UNI-d4749f31-36

Cc1csc2ncc(C(=O)Nc3cccc4ncccc34)c(=O)n12

Cc1nc2cc(NC(=O)Cn3cnc4c(cnn4C)c3=O)ccc2o1

WIL-UNI-2a57d06c-3

Cc1nc2cc(NC(=O)Cn3cnc4c(cnn4C)c3=O)ccc2o1

3-aminopyridine-like Assayed Check Availability on Manifold View
Cc1cc2ncc(C(=O)Nc3ccc4oc(C)nc4c3)c(C)n2n1

WIL-UNI-2a57d06c-4

Cc1cc2ncc(C(=O)Nc3ccc4oc(C)nc4c3)c(C)n2n1

CC1NCCn2c(-c3nc(-c4cnc5cnccn45)no3)ccc21

WIL-UNI-2a57d06c-5

CC1NCCn2c(-c3nc(-c4cnc5cnccn45)no3)ccc21

Cc1cccc2nc(NC3CCN(c4ccc5nncn5n4)C3)sc12

WIL-UNI-2a57d06c-6

Cc1cccc2nc(NC3CCN(c4ccc5nncn5n4)C3)sc12

Cn1ncc2cc(C(=O)NNc3nc4cccnc4s3)cnc21

WIL-UNI-2a57d06c-7

Cn1ncc2cc(C(=O)NNc3nc4cccnc4s3)cnc21

Cc1nc2ccc(NS(=O)(=O)c3cccc4nonc34)cc2o1

WIL-UNI-2a57d06c-8

Cc1nc2ccc(NS(=O)(=O)c3cccc4nonc34)cc2o1

Cc1nc2c(C(=O)Nc3cccc4[nH]c(=O)oc34)cccc2o1

WIL-UNI-2a57d06c-9

Cc1nc2c(C(=O)Nc3cccc4[nH]c(=O)oc34)cccc2o1

Cc1nc2sccn2c1CN(C)C(=O)c1cnc2sccn2c1=O

WIL-UNI-2a57d06c-10

Cc1nc2sccn2c1CN(C)C(=O)c1cnc2sccn2c1=O

CC(NCc1cnc2c(cnn2C)c1)c1nc2ccccc2s1

WIL-UNI-2a57d06c-11

CC(NCc1cnc2c(cnn2C)c1)c1nc2ccccc2s1

Cc1cn2c(CNC(=O)c3ccc4nccnc4c3)c(C)nc2s1

WIL-UNI-2a57d06c-12

Cc1cn2c(CNC(=O)c3ccc4nccnc4c3)c(C)nc2s1

Cc1nc2ccc(NCc3cnc4ccccn34)cn2n1

WIL-UNI-2a57d06c-13

Cc1nc2ccc(NCc3cnc4ccccn34)cn2n1

Cc1nn(C)c2ncc(NC(=O)c3ccnc4c3nnn4C)cc12

WIL-UNI-2a57d06c-14

Cc1nn(C)c2ncc(NC(=O)c3ccnc4c3nnn4C)cc12

Cc1ccn2ncc(C(=O)NC(C)c3nnc4c(=O)[nH]ccn34)c2n1

WIL-UNI-2a57d06c-15

Cc1ccn2ncc(C(=O)NC(C)c3nnc4c(=O)[nH]ccn34)c2n1

O=C(NCc1nnc2c(=O)[nH]ccn12)c1ccnc2ccnn12

WIL-UNI-2a57d06c-16

O=C(NCc1nnc2c(=O)[nH]ccn12)c1ccnc2ccnn12

Cn1c(=O)oc2cc(CNc3ccc4scnc4c3)ccc21

WIL-UNI-2a57d06c-17

Cn1c(=O)oc2cc(CNc3ccc4scnc4c3)ccc21

O=C(NNc1nc2cccnc2s1)c1ccc2ccncc2c1

WIL-UNI-2a57d06c-18

O=C(NNc1nc2cccnc2s1)c1ccc2ccncc2c1

Cn1ncc2c(NCc3ccc4cccnc4c3)ncnc21

WIL-UNI-2a57d06c-19

Cn1ncc2c(NCc3ccc4cccnc4c3)ncnc21

Cc1cnc2nc(C(=O)Nc3nc4cc(Br)ccn4n3)nn2c1

WIL-UNI-2a57d06c-20

Cc1cnc2nc(C(=O)Nc3nc4cc(Br)ccn4n3)nn2c1

O=C(Cc1csc2nccn12)Nc1nc2ccccc2s1

WIL-UNI-2a57d06c-21

O=C(Cc1csc2nccn12)Nc1nc2ccccc2s1

3-aminopyridine-like Made Check Availability on Manifold View
Cn1cc(-c2nn(C)cc2NC(=O)c2ccn3nccc3n2)cn1

WIL-UNI-2a57d06c-22

Cn1cc(-c2nn(C)cc2NC(=O)c2ccn3nccc3n2)cn1

Cc1nc2ccc(C(=O)Nc3nn4cnnc4s3)cc2nc1C

WIL-UNI-2a57d06c-23

Cc1nc2ccc(C(=O)Nc3nn4cnnc4s3)cc2nc1C

Cc1noc2ncc(NS(=O)(=O)c3cnc4onc(C)c4c3)cc12

WIL-UNI-2a57d06c-24

Cc1noc2ncc(NS(=O)(=O)c3cnc4onc(C)c4c3)cc12

O=C(c1ccc2nnnn2c1)N1CCn2c(cc3ccccc32)C1

WIL-UNI-2a57d06c-25

O=C(c1ccc2nnnn2c1)N1CCn2c(cc3ccccc32)C1

Cc1cc(Nc2ccc3nc(C)sc3c2)n2ncnc2n1

WIL-UNI-2a57d06c-26

Cc1cc(Nc2ccc3nc(C)sc3c2)n2ncnc2n1

Cn1cc(-c2cccc(NC(=O)c3ccc4nnnn4c3)c2)nn1

WIL-UNI-2a57d06c-27

Cn1cc(-c2cccc(NC(=O)c3ccc4nnnn4c3)c2)nn1

CC(NCc1cnc2ccccn12)c1nnc2ccccn12

WIL-UNI-2a57d06c-28

CC(NCc1cnc2ccccn12)c1nnc2ccccn12

Cc1cc(C)n2ncc(C(=O)Nc3ccc4ncsc4c3)c2n1

WIL-UNI-2a57d06c-29

Cc1cc(C)n2ncc(C(=O)Nc3ccc4ncsc4c3)c2n1

Cc1cc(C(=O)Nc2cccc3nonc23)c2c(C)noc2n1

WIL-UNI-2a57d06c-30

Cc1cc(C(=O)Nc2cccc3nonc23)c2c(C)noc2n1

O=C(Nc1ccc2nccnc2c1)c1csc2cncn12

WIL-UNI-2a57d06c-31

O=C(Nc1ccc2nccnc2c1)c1csc2cncn12

Cc1cc2c(N3CCc4[nH]c5ccccc5c4C3)nccn2n1

WIL-UNI-2a57d06c-32

Cc1cc2c(N3CCc4[nH]c5ccccc5c4C3)nccn2n1

Cc1cn2nc(NCc3ccc4ncccc4c3)sc2n1

WIL-UNI-2a57d06c-33

Cc1cn2nc(NCc3ccc4ncccc4c3)sc2n1

Cc1ccc2nnc(CNc3ccc4nnc(C(F)(F)F)n4n3)n2c1

WIL-UNI-2a57d06c-34

Cc1ccc2nnc(CNc3ccc4nnc(C(F)(F)F)n4n3)n2c1

Cc1nc2ccc(NC(=O)Cn3ncn4nccc4c3=O)cc2s1

WIL-UNI-2a57d06c-35

Cc1nc2ccc(NC(=O)Cn3ncn4nccc4c3=O)cc2s1

3-aminopyridine-like Assayed Check Availability on Manifold View
Cc1cc2nccc(NC(=O)NCc3nc4ccccc4s3)n2n1

WIL-UNI-2a57d06c-36

Cc1cc2nccc(NC(=O)NCc3nc4ccccc4s3)n2n1

Cc1ccc2ncnc(NCc3ccc4nonc4c3)c2c1

WIL-UNI-2a57d06c-37

Cc1ccc2ncnc(NCc3ccc4nonc4c3)c2c1

O=C(NNc1cc(O)nc2ncccc12)c1ccnc2ccccc12

WIL-UNI-2a57d06c-38

O=C(NNc1cc(O)nc2ncccc12)c1ccnc2ccccc12

CC(CNc1ccc2nnnn2n1)c1nc2ccccc2s1

WIL-UNI-2a57d06c-39

CC(CNc1ccc2nnnn2n1)c1nc2ccccc2s1

Cc1nc2ccc(NC(=O)NCc3ccc4[nH]c(=O)[nH]c4c3)cc2o1

WIL-UNI-2a57d06c-40

Cc1nc2ccc(NC(=O)NCc3ccc4[nH]c(=O)[nH]c4c3)cc2o1

Cn1ncc2c(=O)[nH]c(NNC(=O)c3cccn4nccc34)nc21

WIL-UNI-2a57d06c-41

Cn1ncc2c(=O)[nH]c(NNC(=O)c3cccn4nccc34)nc21

CC(NC(=O)Nc1ccn2ccnc2c1)c1ccc2[nH]c(=O)oc2c1

WIL-UNI-2a57d06c-42

CC(NC(=O)Nc1ccn2ccnc2c1)c1ccc2[nH]c(=O)oc2c1

Cn1ccn2c(CNc3nc4ccccc4s3)nnc2c1=O

WIL-UNI-2a57d06c-43

Cn1ccn2c(CNc3nc4ccccc4s3)nnc2c1=O

Cc1nn2c(CNc3ccc4oc(=O)n(C)c4c3)c(C)nc2s1

WIL-UNI-2a57d06c-44

Cc1nn2c(CNc3ccc4oc(=O)n(C)c4c3)c(C)nc2s1

Cc1nc2cc(C(=O)NNc3ccnc4cccnc34)ccc2o1

WIL-UNI-2a57d06c-45

Cc1nc2cc(C(=O)NNc3ccnc4cccnc34)ccc2o1

O=C(Nc1cnc2ccnn2c1)c1cc(Br)cn2ccnc12

WIL-UNI-2a57d06c-46

O=C(Nc1cnc2ccnn2c1)c1cc(Br)cn2ccnc12

Cn1c(NCc2cn3ccnc3s2)nc2ccccc21

WIL-UNI-2a57d06c-47

Cn1c(NCc2cn3ccnc3s2)nc2ccccc21

CC(C(=O)Nc1cccc2nccnc12)n1cnc2c(N)ncnc21

WIL-UNI-2a57d06c-48

CC(C(=O)Nc1cccc2nccnc12)n1cnc2c(N)ncnc21

3-aminopyridine-like Assayed Check Availability on Manifold View
O=C(Nc1ccc2nncn2c1)c1ccc2scnc2c1

WIL-UNI-2a57d06c-49

O=C(Nc1ccc2nncn2c1)c1ccc2scnc2c1


Design Rationale:

Fragment merging

Discussion: