Submission Details

Molecule(s):
Cn1nnc(NC(=O)Cc2cccc(Cl)c2)n1

VLA-UNK-411a133b-1

Cn1nnc(NC(=O)Cc2cccc(Cl)c2)n1

3-aminopyridine-like Check Availability on Manifold View
Cn1nnnc1NC(=O)Cc1cccc(Cl)c1

VLA-UNK-411a133b-2

Cn1nnnc1NC(=O)Cc1cccc(Cl)c1

3-aminopyridine-like Check Availability on Manifold View

Design Rationale:

Isoquinoline replacements based on an active analog (50uM) that was previously unexplored.

Other Notes:

Both available from Enamine: s_11____7425710____3020516 s_11____8331846____3020516

Discussion: