Submission Details

VLA-UCB-1dbca3b4
Molecule(s):
O=C(Cc1cccc(Cl)c1)NC1C(=O)Nc2ccccc21

VLA-UCB-1dbca3b4-1

O=C(Cc1cccc(Cl)c1)NC1C(=O)Nc2ccccc21

O=C(Cc1cccc(Cl)c1)Cn1c(=O)[nH]c2ccccc21

VLA-UCB-1dbca3b4-2

O=C(Cc1cccc(Cl)c1)Cn1c(=O)[nH]c2ccccc21

3-aminopyridine-like Check Availability on Manifold View
O=C1CN(c2cccc(Cl)c2)C(=O)N1c1cncc2ccccc12

VLA-UCB-1dbca3b4-3

O=C1CN(c2cccc(Cl)c2)C(=O)N1c1cncc2ccccc12

3-aminopyridine-like Check Availability on Manifold View
Cc1ccncc1N1C(=O)CC(c2cccc(Cl)c2)C1=O

VLA-UCB-1dbca3b4-4

Cc1ccncc1N1C(=O)CC(c2cccc(Cl)c2)C1=O

3-aminopyridine-like Check Availability on Manifold View
O=C1CC(c2cccc(Cl)c2)C(=O)C1n1c(=O)[nH]c2ccccc21

VLA-UCB-1dbca3b4-5

O=C1CC(c2cccc(Cl)c2)C(=O)C1n1c(=O)[nH]c2ccccc21

3-aminopyridine-like Check Availability on Manifold View
O=C1CC(c2cccc(Cl)c2)C(=O)N1c1cncc2ccccc12

VLA-UCB-1dbca3b4-6

O=C1CC(c2cccc(Cl)c2)C(=O)N1c1cncc2ccccc12

3-aminopyridine-like Check Availability on Manifold View
O=C1Nc2ccccc2C1N1C(=O)CC(c2cccc(Cl)c2)C1=O

VLA-UCB-1dbca3b4-7

O=C1Nc2ccccc2C1N1C(=O)CC(c2cccc(Cl)c2)C1=O

O=C1CC(c2cccc(Cl)c2)C(=O)N1c1cccc2[nH]ncc12

VLA-UCB-1dbca3b4-8

O=C1CC(c2cccc(Cl)c2)C(=O)N1c1cccc2[nH]ncc12

3-aminopyridine-like Check Availability on Manifold View
O=C1CN(c2cccc(Cl)c2)C(=O)N1c1cccc2[nH]ncc12

VLA-UCB-1dbca3b4-9

O=C1CN(c2cccc(Cl)c2)C(=O)N1c1cccc2[nH]ncc12

3-aminopyridine-like Check Availability on Manifold View
O=C1CCC(c2cccc(Cl)c2)C(=O)N1c1cncc2ccccc12

VLA-UCB-1dbca3b4-10

O=C1CCC(c2cccc(Cl)c2)C(=O)N1c1cncc2ccccc12

3-aminopyridine-like Check Availability on Manifold View
O=C1NC(c2cccc(Cl)c2)C(=O)N1c1cccc2[nH]ncc12

VLA-UCB-1dbca3b4-11

O=C1NC(c2cccc(Cl)c2)C(=O)N1c1cccc2[nH]ncc12

3-aminopyridine-like Check Availability on Manifold View
O=C1C(c2cccc(Cl)c2)N(CC2CCCCC2)C(=O)N1c1cncc2ccccc12

VLA-UCB-1dbca3b4-12

O=C1C(c2cccc(Cl)c2)N(CC2CCCCC2)C(=O)N1c1cncc2ccccc12

3-aminopyridine-like Check Availability on Manifold View
O=C1CCN(c2cccc(Cl)c2)C(=O)N1c1cncc2ccccc12

VLA-UCB-1dbca3b4-13

O=C1CCN(c2cccc(Cl)c2)C(=O)N1c1cncc2ccccc12

3-aminopyridine-like Check Availability on Manifold View
CC1(C(=O)Nc2cncc3ccccc23)C(=O)COc2ccc(Cl)cc21

VLA-UCB-1dbca3b4-14

CC1(C(=O)Nc2cncc3ccccc23)C(=O)COc2ccc(Cl)cc21

3-aminopyridine-like Check Availability on Manifold View
O=C(Nc1cncc2ccccc12)C1CCOc2ccc(Cl)cc21

VLA-UCB-1dbca3b4-15

O=C(Nc1cncc2ccccc12)C1CCOc2ccc(Cl)cc21

3-aminopyridine-like Assayed Check Availability on Manifold View
O=C1COc2ccc(Cl)cc2C1C(=O)Nc1cncc2ccccc12

VLA-UCB-1dbca3b4-16

O=C1COc2ccc(Cl)cc2C1C(=O)Nc1cncc2ccccc12

3-aminopyridine-like Check Availability on Manifold View
O=C1NC(c2cccc(Cl)c2)C(=O)N1c1cncc2ccccc12

VLA-UCB-1dbca3b4-17

O=C1NC(c2cccc(Cl)c2)C(=O)N1c1cncc2ccccc12

3-aminopyridine-like Check Availability on Manifold View
O=C1NCC(c2cccc(Cl)c2)C(=O)N1c1cncc2ccccc12

VLA-UCB-1dbca3b4-18

O=C1NCC(c2cccc(Cl)c2)C(=O)N1c1cncc2ccccc12

3-aminopyridine-like Check Availability on Manifold View
Design Rationale:

Designs based on ADA-UCB-6c2cb422-1

Discussion:

Contributor: Vladas Oleinikovas, UCB - Mon, 10 Aug 2020 14:00:37 +0000