CNC(=O)CN1Cc2ccc(Cl)cc2[C@]2(C1)NC(=O)N(c1cncc3ccccc13)C2=O
NC(=O)CN1Cc2ccc(Cl)cc2[C@]2(C1)NC(=O)N(c1cncc3ccccc13)C2=O
O=C1N[C@]2(CNCc3ccc(Cl)cc32)C(=O)N1c1cncc2ccccc12
Improving potency of spirocycles based on MAT-POS-4223bc15-23. Enantiomers of the previous submission (VLA-MRT-8c78ee15). I think these are the more active steroisomers.
I think the stereochemistry is incorrectly labelled for VLA-UNK-cf7facf1-1 / VLA-UCB-34f3ed0c-11 enantiomer pair.