Submission Details

Molecule(s):
O=C(CCl)N1CCN(C(=O)Nc2ccccc2O)CC1

SWA-SYN-6423ea73-1
Duplicate of:
SWA-SYN-d2e6fa14-1

O=C(CCl)N1CCN(C(=O)Nc2ccccc2O)CC1

Duplicate piperazine-chloroacetamide Check Availability on Manifold View
O=C(CCl)N1CCN(S(=O)(=O)Nc2ccccc2O)CC1

SWA-SYN-6423ea73-2
Duplicate of:
SWA-SYN-d2e6fa14-2

O=C(CCl)N1CCN(S(=O)(=O)Nc2ccccc2O)CC1

Duplicate piperazine-chloroacetamide Check Availability on Manifold View
O=C(Cn1cccn1)N1CCN(C(=O)Nc2ccccc2O)CC1

SWA-SYN-6423ea73-3
Duplicate of:
SWA-SYN-d2e6fa14-3

O=C(Cn1cccn1)N1CCN(C(=O)Nc2ccccc2O)CC1

O=C(Cc1c[nH]c2ncccc12)N1CCN(S(=O)(=O)c2c(F)cccc2F)CC1

SWA-SYN-6423ea73-4
Duplicate of:
SWA-SYN-d2e6fa14-4

O=C(Cc1c[nH]c2ncccc12)N1CCN(S(=O)(=O)c2c(F)cccc2F)CC1

CNC(=O)NS(=O)(=O)N1CCN(C(=O)CCl)CC1

SWA-SYN-6423ea73-5
Duplicate of:
SWA-SYN-d2e6fa14-5

CNC(=O)NS(=O)(=O)N1CCN(C(=O)CCl)CC1

Duplicate piperazine-chloroacetamide Check Availability on Manifold View
O=C(NS(=O)(=O)N1CCN(C(=O)CCl)CC1)c1ncccn1

SWA-SYN-6423ea73-6
Duplicate of:
SWA-SYN-d2e6fa14-6

O=C(NS(=O)(=O)N1CCN(C(=O)CCl)CC1)c1ncccn1

Duplicate piperazine-chloroacetamide Check Availability on Manifold View
N#Cc1ccc(CNC(=O)N2CCN(C(=O)CCl)CC2)cc1

SWA-SYN-6423ea73-7
Duplicate of:
SWA-SYN-d2e6fa14-7

N#Cc1ccc(CNC(=O)N2CCN(C(=O)CCl)CC2)cc1

Duplicate piperazine-chloroacetamide Check Availability on Manifold View
O=C(Cn1cccn1)Nc1cccc(N2CCCS2(=O)=O)c1

SWA-SYN-6423ea73-8
Duplicate of:
SWA-SYN-d2e6fa14-8

O=C(Cn1cccn1)Nc1cccc(N2CCCS2(=O)=O)c1

Duplicate 3-aminopyridine-like Check Availability on Manifold View
O=C(CCl)Nc1cccc(N2CCCS2(=O)=O)c1

SWA-SYN-6423ea73-9
Duplicate of:
SWA-SYN-d2e6fa14-10

O=C(CCl)Nc1cccc(N2CCCS2(=O)=O)c1

O=C(Cc1c[nH]c2ncccc12)N1CCC(N2CCCS2(=O)=O)CC1

SWA-SYN-6423ea73-10
Duplicate of:
SWA-SYN-d2e6fa14-9

O=C(Cc1c[nH]c2ncccc12)N1CCC(N2CCCS2(=O)=O)CC1


Design Rationale:

By eye, bioisosterism

Inspired By:
Discussion: